Recognition and results
Healthy Longevity Clinic's program reached the Top 40 of XPRIZE Healthspan. In a small proof-of-concept study, statistically significant pre/post changes were detectable within eight weeks.
Healthy Longevity Clinic was a 2025 XPRIZE Healthspan Milestone 1 award recipient. The program evaluated in the competition combined a measured starting point, coordinated care and repeat measurement. Each client’s plan is adapted to their health, priorities and clinical assessment.
Several measures showed statistically significant pre/post improvement during the eight-week program, including a DNA-methylation pace-of-aging measure, HbA1c and Timed Up and Go. The short study window is practically encouraging: progress was measurable in weeks, supporting earlier reassessment during care. This was a single-arm study with 10 participants and no randomized control group. It cannot prove that the program caused every change or predict how quickly an individual client will improve.
The source report describes a prospective, single-arm, open-label, within-participant pre/post feasibility evaluation. Ten participants completed an eight-week multimodal programme. Mean age at baseline was 78.1 years (range 71–84); seven participants were women and three were men. There was no randomized control group.
The report used paired pre/post analysis for each endpoint, 95% confidence intervals, paired effect sizes and exact sign-flip permutation tests. The number of paired observations varied from seven to ten for some measures. The primary table reports unadjusted p-values across many endpoints, so individual findings need cautious interpretation.
All ten enrolled participants completed the programme and the report recorded no serious adverse events or post-enrolment withdrawals. It also recorded mild transient fatigue in several participants early in training. This small, selected cohort cannot establish safety for a wider population or for each component of the combined programme.
Study summary
Our research team answers scientific questions about the evaluation, its design and its limitations.
